Efficacy and Safety of Pulpal Anesthesia Strategies during Endodontic Treatment of Permanent Mandibular Molars with Symptomatic Irreversible Pulpitis: A Systematic Review and Network Meta-analysis

5 (1 vote)

CE Hours: 1.0 CE hour

Several strategies have been investigated for achieving successful pulpal anesthesia during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis. However, comprehensive evaluation and identification of the most efficacious and safe intervention are lacking. We aimed to determine this using network meta-analysis.

At the conclusion, participants should be able to:

  • Identify the most effective and safe approaches to achieve successful pulpal anesthesia during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.
  • Avoid ineffective strategies to achieve anesthesia when the primary injection fails during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.
  • Identify the most effective preoperative pharmacological approach to manage pain during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.

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7 Questions
CE Test
5 Questions  |  Unlimited attempts  |  4/5 points to pass
5 Questions  |  Unlimited attempts  |  4/5 points to pass
Certificate
1.00 CE credit  |  Certificate available
1.00 CE credit  |  Certificate available

Maryam Zanjir, DDS

Nima Laghapour Lighvan, HBSc

Carilynne Yarascavitch, BSc, DDS, MSc, Dip. ADBA

Joseph Beyene, BSc, MSc, PhD

Prakesh S. Shah, MSc, MBBS, MD, DCH, MRCP, FRCPC

Amir Azarpazhooh, D.D.S., M.Sc., Ph.D., F.R.C.D.(C)

Dr. Amir Azarpazhooh received his DDS from Iran (2001), his speciality training at the University of Toronto (UofT) in Dental Public Health (2007) and endodontics (2010), followed by his PhD in 2011. He is a UofT full-time tenured Associate Professor, with cross-appointments to the Clinical Epidemiology Program at the Institute of Health Policy, Management and Evaluation, Faculty of Medicine, and Toronto Health Economics and Technology Assessment Collaborative, UofT. He is also the Head of both Divisions of Endodontics and Research at the Department of Dentistry, Mount Sinai Hospital, Toronto.

Currently, his attributed grants and awards total more than CDN $1.25M and these have enabled him to manage a strong group of graduate students over the years. To date, he has been an editor of a textbook on evidence-based dentistry, has published six book chapters, and more than 150 papers, abstracts and reports and has presented at over 50 national and international scientific meetings. He has been awarded nationally and internationally, by the Cochrane Canada, the Canadian Academy of Endodontics, and the American Association of Endodontists. He is an Associate Editor of the Journal of Endodontics.

Amir is a practicing endodontist, with part-time private practices in Toronto as well as a hospital practice in Mount Sinai Hospital providing endodontic care to patients when their medical, physical or mental status indicates the need for a hospital environment. Despite his heavy load of teaching, research and clinical practice, out of the office he enjoys life with his wife, travelling, cycling, photography, and gardening.

We would like to thank Mrs. Maria Zych from the University of Toronto Libraries for her help in conducting the search. The authors deny anyconflicts of interest related to this study. There was no funding associated with this pape