I-8 Pain Perspectives – a Conversation Between Three Generations of Pain Gurus

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Just as clinicians have “pedigrees” arising from their particular training program, so do scientists. In this session, three generations of clinician pain scientists will describe research advances in clarifying mechanisms of dental and other orofacial pain conditions and their control, as well as evolving concepts related to pain transmission, plasticity, diagnosis and treatment. The evolution of the definition of pain beyond the binary (pain is present or not), and rather as a complex multidimensional biopsychosocial concept, will be discussed. Endodontists are experts in acute pain management. As it is now clear that there is a continuum between acute and chronic pain, there is even a stronger impetus to develop best practices for minimizing the experience of severe acute pain, without the use of opioid analgesics. The role of the endodontist in preventing and interrupting the transition to chronic pain will be explored. Several case-based studies will also be presented to guide the discussion. The goal is to provide both context and recommendations for accurate diagnosis and successful management of acute and chronic intraoral pain.

At the conclusion, participants should be able to:

  • Describe the concepts of peripheral sensitization and central sensitization and how the expression and control of these processes influence diagnosis and treatment.
  • Describe approaches to gain effective analgesia or anesthesia, with minimal use of opioid analgesics given the impact of the opioid overdose epidemic on clinician management strategies.
  • Recognize acute pain as a risk factor for the development of chronic pain and utilize clinical strategies relevant to the endodontic practice to help patients who present with persistent pain after root canal treatment.
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Kenneth Hargreaves, D.D.S., Ph.D.

Ken Hargreaves received his DDS from Georgetown University, his PhD in physiology from the Uniformed Services University of the Health Sciences in Bethesda, MD, and his certificate in Endodontics from the University of Minnesota. Ken spent 5 years at the Pain Clinic of the NIDCR and 7 years as an associate professor of Endodontics and Pharmacology at the University of Minnesota. He joined the University of Texas Health Science Center at San Antonio in 1997, as professor and Chair of the Department of Endodontics and is cross-appointed as professor in the Departments of Pharmacology, Physiology and Surgery in the Medical School. He maintains a private practice limited to endodontics and is a Diplomate of the American Board of Endodontists. Ken has received an NIH MERIT Award for research, two IADR Distinguished Scientist Awards, the ADA Gold Medal for Research and the Louis I. Grossman Award from the AAE. He has published more than 190 articles and, with Harold Goodis and Frank Tay, co-edited the 2nd edition Seltzer and Bender’s Dental Pulp, and, with Lou Berman, co-edited the 11th edition of Cohen’s Pathways of the Pulp. Ken also serves as editor of the Journal of Endodontics.

Speaker Disclosure: 

I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation

Jennifer L. Gibbs, MS, DDS, PhD

Jennifer L. Gibbs, M.A.S, D.D.S., Ph.D. is Director of the Endodontics Division and Program Director of Advanced Graduate Education Program in Endodontics and an Associate Professor at Harvard School of Dental Medicine

Dr. Gibbs received her dental degree and her Ph.D. in Pharmacology from the University of Texas Health Science Center San Antonio. She then completed a certificate in Endodontics and an M.A.S. in Clinical Research from the University of California San Francisco, as well as a postdoctoral training period. She is now a full time faculty at Harvard.

Dr. Gibbs heads a translational research group focused on understanding the neurobiological mechanisms of orofacial pain with a focus on dental pain, and patient centered outcomes of endodontic treatments. She teaches clinically in the advanced graduate Endodontic Program and lectures to both post-graduate and pre-doctoral students. Dr. Gibbs cares for patients at the Faculty Practice at Harvard. She is a past Educator Fellow of the American Association of Endodontics.

Disclosure

In accordance with this policy, I declare that I have NO past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith.

Raymond Dionne, D.D.S., M.S. Ph.D.

Dr. Dionne received a DDS from Georgetown University and a PhD from the Medical College of Virginia. He conducted clinical and translational pain research at the National Institute of Dental and Craniofacial Research for 34 years, as well as practiced dentistry part-time in the District of Columbia. He is currently a restless retiree living in Missouri.

Speaker Disclosure

In accordance with this policy, I declare I have a past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith, as indicated: AIM Targeted Therapeutics: Consultant on preclinical development of an investigational analgesic formulation (Ongoing); Rilento Pharma: consultant for pre-clinical development of investigational analgesic formulation (Ongoing)

Barry J. Sessle, B.D.S., M.D.S. Ph.D., D.Sc.(hc)

Dr. Barry J. Sessle is professor, Faculties of Dentistry and Medicine, University of Toronto. He was dean of the Faculty of Dentistry from 1990-2001. He is an elected Fellow of the Royal Society of Canada, a member of the Canadian Academy of Science, and a Fellow of the Canadian Academy Of Health Sciences. He has served as president of the International Association for the Study of Pain, the International Association for Dental Research, the Canadian Pain Society and the Canadian Association for Dental Research. His research on craniofacial pain and neuromuscular function has been supported for more than 40 years by both NIH and the Canadian Institutes of Health Research. He has published 12 books and 450 journal articles and book chapters, and delivered more than 450 invited presentations world-wide.

Raymond Dionne, D.D.S., Ph.D.

I declare that I have proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.NO DISCLOSURE INFORMATION SUBMITTED

Kenneth M. Hargreaves, D.D.S., Ph.D.

I declare that I have proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.Vindolor (Self) : CSO (Status: Ongoing), Stockholder/Ownership Interest (excluding diversified mutual funds) (Status: Ongoing)

Jennifer Gibbs, D.D.S., M.S., Ph.D.

I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

Barry J. Sessle, B.D.S., M.D.S. Ph.D., D.Sc.(hc)

I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.