AAE Online CE
SP-59 Where are Dental Pulp Stem Cells in the Pulp? What Can They Do For Us?
Dental pulp stem cells have been discovered for almost 20 years. Since then, various oral stem cells have also been identified which have drawn tremendous attention from the medical and dental community. Particularly, they have led to the establishment of a new discipline in endodontics - regenerative endodontics. However, the education of oral stem cells or stem cells in general in our field is still limited. Starting from the biology courses at the undergraduate level to medical and dental curricula, teaching of stem cell biology has been minimum, if any. Lacking such knowledge may reduce the ability of our clinical judgment in diagnosis, treatment and outcome prediction. This presentation attempts to provide updated knowledge on the current understanding of dental pulp stem cells, oral stem cells and the ongoing research. The following areas will be covered: i) The physical location of oral stem cells in dental tissues. ii) The basic biological properties of oral stem cells and stem cells in general. iii) Oral stem cells for regenerative endodontics. iv) Oral stem cells for medical applications.
At the conclusion, participants should be able to:
- Describe the basic biology of stem cells.
- List various oral stem cells and describe their in situ locations.
- Discuss the clinical relevance of oral stem cells.
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George T-J. Huang, D.D.S., M.S.D., D.Sc.
Dr. Huang is a board certified endodontist, currently Professor and Director for Stem Cells and Regenerative Therapies, Department of Bioscience Research at UTHSC, College of Dentistry. He is the former Chair/Herbert Schilder Professor in Endodontics, at Boston University, also a former Chair in Endodontics at Columbia University. Dr. Huang has published more than 170 research articles, abstracts, review articles, including papers in Stem Cells, Stem Cells and Development, Stem Cell Research and Therapy, Tissue Engineering, Regenerative Medicine, Infection and Immunity, Human Gene Therapy, Journal of Dental Research, Journal of Endodontics, etc; book chapters in books such as Ingle’s Endodontics, Cohen’s Pathways of the Pulp, Endodontic Microbiology, Principles of Regenerative Medicine, Tissue Engineering and Regenerative Dentistry, Tissue-Specific Stem Cell Niche, Material-Tissue Interfacial Phenomena, etc; and co-edited with Dr. Irma Thesleff and wrote chapters for the text book “Stem cells, craniofacial development and regeneration”, in 2013. His research has been funded by various sources including NIH and AAE Foundation.
George T.J. Huang, D.D.S., M.S.D., D.Sc.
I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.