CD-7 Boosting Host Response

4.33 (3 votes)

CE Hours: 1.5


Apical periodontitis should be resolved with a correct root canal treatment which takes care of the infection and promotes healing. Nevertheless, 31-36% of persistent AP has be reported. Many clinical and procedural factors have been correlated to the outcome of endodontic therapy. Furthermore, the systemic health of the patient and the genetic predisposition of the host may also play a role in the healing of apical periodontitis. Some chronic systemic conditions affecting the patients, and new categories of medications (like biologic drugs) offer an interesting insight into unknown aspects of the patient response to endodontic treatment. At the same time, the research is bringing to our attention how future protocols may enhance the healing of AP (following a state-of-the-art root canal treatment ) by complementing endodontic treatment with both systemic and local immuno-modulatory therapies. Most of this research has been already conducted in the periodontal field. Future direction in the overall treatment of AP will be discussed.

  • Define the state-of-the-art treatment outcome for apical periodontitis.
  • Describe the importance of genetic predisposition of the patient and host immune-response on the natural history and response to treatment of apical periodontitis.
  • Discuss the treatment options provided by new immune-modulatory drugs that boost the host response to apical periodontitis.


Open to view video.
9 Questions
CE Test
5 Questions  |  Unlimited attempts  |  4/5 points to pass
5 Questions  |  Unlimited attempts  |  4/5 points to pass
1.50 CE credits  |  Certificate available
1.50 CE credits  |  Certificate available

Elisabetta Cotti, D.D.S., M.S.

Elisabetta Cotti, DDS, MS, received her DDS from the University of Cagliari – Italy and the specialty and MS in Endodontics from the University of Loma Linda- California. She is Full Professor of Conservative Dentistry and Endodontics, and the Chairman of the Department of Conservative Dentistry and Endodontics at the School of Dentistry, University of Cagliari- Italy. She is currently the Director of the Post Graduate programme (Master) in Clinical Endodontics at the University of Cagliari. She teaches in the Advanced Education Programs in Endodontics at the University of Bologna and she is lecturer in the Department of Endodontics at Loma Linda University, USA. She is the Treasuree for IFEA, active member of the AAE, of the Italian Association of Endodontics (SIE), Italian Academy of Endodontics (AIE), of the European Association (ESE). She is the Past President of the Italian Society of Dental Traumatology (SIDT). She practices limited to Endodontics, She is author of several articles and chapters in the field of Endodontics with has a specific interest in apical periodontit

Elisabetta Cotti, D.D.S., M.S.

I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.