Effectiveness of 1-Visit and 2-Visit Endodontic Retreatment of Teeth with Persistent/Secondary Endodontic Infection: A Randomized Clinical Trial with 18 Months of Follow-up

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CE Hours: 1.0

Description: This randomized clinical trial aimed to compare the effectiveness of endodontic retreatment of teeth with posttreatment apical periodontitis (PTAP) performed in 1 visit versus 2 visits on the reduction of cultivable bacteria (colony-forming units [CFUs]), lipopolysaccharides (LPSs), lipoteichoic acid (LTA), and the periapical lesion volume (mm3) after 18 months of follow-up.

  • Compare the effectiveness of endodontic retreatment performed in one visit versus two visits on teeth with post-treatment apical periodontitis (PTAP).
  • Assess the periapical lesion volume (mm3) of teeth with post-treatment apical periodontitis (PTAP) who underwent endodontic retreatment in one or two visits after an 18-month follow-up period.
  • Evaluate the efficacy of endodontic treatment in one or two visits, taking into account microbiological and tomographic features.


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Cassia Cestari Toia, DDS, MSc, PhD

Rayana Duarte Khoury, DDS, MSc,

Bruna Jordao Motta Corazza, DDS, MSc,

Esteban Isai Flores Orozco, DDS, MSc, PhD

Marcia Carneiro Valera, DDS, MSc, PhD