Effects of Diabetes on Elemental Levels and Nanostructure of Root Canal Dentin
CE Hours: 1.0
Description: This study evaluated the effects of diabetes mellitus (DM) on the nanostructure of root canal dentin using high-resolution transmission electron microscopy (HRTEM) and inductively coupled plasma mass spectrometry (ICP-MS).
At the conclusion of this article, the reader will be able to:
- Evaluate the impact of diabetes mellitus on the elemental composition of dentin, with a focus on copper (Cu), lithium (Li), zinc (Zn), selenium (Se), strontium (Sr), manganese (Mn), and magnesium (Mg)
- Describe the nanostructural differences in dentin between diabetic and non-diabetic patients, as observed through high-resolution transmission electron microscopy (HRTEM)
- Discuss the potential consequences of altered dentin composition and nanostructure in diabetic patients for root canal treatment outcomes
Mohammad Ali Saghiri, DEng, MS, PhD
MA Saghiri holds PhD degrees in biomedical engineering and medical laboratories, specializing in dental materials and medical devices. During his tenure as a visiting scholar at the University of Michigan School of Dentistry, he collaborated under the guidance of the late Prof. Kamal Asgar, contributing to over 20 published articles. Dr. Saghiri commenced his academic career as an Assistant Professor of Dental Materials at Azad Dental School in 2012, eventually advancing to the position of Associate Professor and IT head. Returning to the US in 2013, he joined Prof. Nader Sheibani’s Lab as an Assistant Scientist in the Department of Ophthalmology and Visual Sciences. Following the completion of postdoctoral studies, he transitioned to Philips Inc. as a Clinical and Biological Scientist, focusing on cutting-edge technology for oral hygiene care until 2018. Currently, Dr. Saghiri serves as the Director of the Biomaterials Research Center and an Assistant Professor in the Department of Restorative Dentistry at Rutgers School of Dental Medicine. Additionally, he holds the position of Adjunct Assistant Professor in the Department of Endodontics at the University of the Pacific School of Dentistry. With a prolific publication record, Dr. Saghiri has authored and co-authored over 130 articles in peer-reviewed dental journals spanning scientific, research, educational, and clinical themes. Recognized for his exceptional contributions, he received three awards at Azad Dental School and is the recipient of the NSF-DMR-2312680, NSF-STTR- 2321456 Awards, along with several other accolades such as TechAdvance and NJ ACT. Notably, he was honored with the DenburTech Award, a distinction reserved for clinical scientists under 40 who have published over 100 articles in the field.
Julia Vakhnovetsky, BS
Julia Vakhnovetsky has a BS degree from Rutgers University with a major in Biological Sciences. She is currently a dental student at the University of Michigan School of Dentistry. She has authored and co-authored over 15 articles in peer-reviewed dental journals that address scientific, research, educational, and clinical topics in endodontics, oral hygiene, dentinal health, diabetes, and artificial intelligence.
Elham Samadi, DDS
Elham Samadi is an international dentist who recently joined the Biomaterials Research Lab at Rutgers School of Dental Medicine. Her focus is on the impact of various systemic diseases on the quality of dentin and the longevity of dental treatments, with a particular interest in diabetes mellitus.
Salvatore Napoli, DDS, MD, FACS
Salvatore Napoli received his DDS degree from Columbia University School of Dental and Oral Surgery in 1979. He then pursued residency programs in dental anesthesiology and oral and maxillofacial surgery from 1980 to 1986. Presently, Dr. Napoli is board certified in oral & maxillofacial surgery (OMFS), a licensed physician (MD), Fellow of the American College of Surgeons and Associate Professor at Rutgers University School of Dental Medicine. He serves as Director of Predoctoral Education in Oral & Maxillofacial Surgery as well as in OMFS Clinic I, OMFS Clinic II, Complicated Exodontia and Advanced Techniques of Pain Control. Additionally, he is an Associate lecturer in topics such as management of patients with cardiovascular disease, allergic reactions, medical and respiratory emergencies, endocrine disorders, and oral pathology.
Fatereh Samadi, DDS
Fatereh Samadi, an accomplished international dentist, has recently become a member of the Biomaterials Research Lab at Rutgers School of Dental Medicine. With over a decade of experience in private practice, specializing in orthodontics, she brings a wealth of knowledge to her current role. Her expertise extends to the evaluation of innovative polyurethane-based sealers in the realm of orthodontic and endodontic biomaterials. During her extensive tenure in private practice, She has authored more than eight articles. Her dedication and contributions have not gone unnoticed, as evidenced by the multiple awards she has received for her outstanding work in private practice.
Michael Conte, DMD, MPH
Michael Conte received his DMD from Rutgers School of Dental Medicine and completed his MPH at Rutgers. He is the Senior Associate Dean for the office of Clinical Affairs and is a Full Professor in the Department of Restorative Dentistry. Dr Conte serves as Medical Director of Rutgers School of Dental Medicine as well as the Director of Infection Control and Environmental Safety. Dr. Conte also oversees the dental school's Office of Facilities and the school Extramural Programs. Dr. Conte is a highly respected dentist and educator.
Steven M. Morgano, DMD
Steven M. Morgano is a fellow of the American College of Prosthodontists, a past president of the Massachusetts section, and has been a member of the College since 1979. He has taught at eight different dental schools, including Boston University and Harvard School of Dental Medicine, and at universities in Kuwait and Dubai. He is currently a professor and chairman of the Department of Restorative Dentistry at Rutgers School of Dental Medicine. Dr. Morgano received his DMD degree from Tufts University School of Dental Medicine, completed his General Practice Residency at Philadelphia General Hospital, and received his specialty certificate in prosthodontics from the Hines Veterans Affairs Medical Center in 1979. Dr. Morgano is also a Diplomate of the American Board of Prosthodontics and has authored and co-authored over 90 articles in numerous dental journals.