Ibuprofen and Acetaminophen Versus Intranasal Ketorolac (Sprix) in an Untreated Endodontic Pain Model: A Randomized, Double-blind Investigation
CE Hours: 1.0 CE hour
Previously, ketorolac was available for primary use only via intravenous and intramuscular routes. Its availability in intranasal form offers an alternative route of administration that patients can self-administer. The purpose of this study was to compare the efficacy of intranasal ketorolac (Sprix; Egalet US Inc, Wayne, PA) with a combination of ibuprofen/acetaminophen in an acute pain model of untreated endodontic patients experiencing moderate to severe pain and symptomatic apical periodontitis.
At the conclusion, participants should be able to:
- Identify intranasal ketorolac as a pain management medication.
- Discuss the effectiveness of intranasal ketorolac in an untreated endodontic pain model.
- Discuss the effectiveness ibuprofen/acetaminophen in an untreated endodontic pain model.
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Kathryn Watts, DMD, MS
Stephen Balzer, DDS, MS
Melissa Drum, DDS, MS
Dr. Drum received her DDS from the University of Minnesota and her endodontic certificate/master's degree from The Ohio State University. She teaches at the dental student and resident levels and is the Advanced Endodontic Program Director and past Predoctoral Endodontic/Emergency Clinic Director. Dr. Drum is active in service at the college, state and national levels and is a full tenured professor. She has published more than 80 articles, multiple book chapters, and coauthored a book. Dr. Drum became a Diplomate of the ABE in 2008 and is currently a Director and President of the ABE. She was named holder of the Al Reader Endowed Professorship in 2013. Dr. Drum received the AAE Edward M. Ostetek Award in 2014 as well as numerous local teaching and research awards over the years. Dr. Drum hates writing and reading bios and is much more fun than this paragraph describes.
John Nusstein, DDS, MS
Dr. John Nusstein is a tenured Professor and the Chair of the Division of Endodontics at The Ohio State University College of Dentistry in Columbus, Ohio.
Al Reader, DDS, MS
Dr. Al Reader is a Professor in the Division of Endodontics and is a previous program director of Advanced Endodontics at the The Ohio State University.
Sara Fowler, DMD, MS
Dr. Sara Fowler received her DMD from the University of Nevada Las Vegas School of Dental Medicine, a graduate of the school’s inaugural class. A native of Columbus, Ohio, Dr. Fowler returned to complete post-graduate training at The Ohio State University College of Dentistry, first with a General Practice Residency, followed by Endodontic Fellowship, and Advanced Endodontic Residency. After working in private practice, Dr. Fowler returned to teach at Ohio State and is now an Associate Professor with tenure in the Division of Endodontics. She is the director of Predoctoral Endodontics and the Emergency Dental Care Clinic, maintains private practice in the Ohio State Dental Faculty Practice, and actively participates in teaching and research with the Advanced Endodontic Residency Program.
Disclosure:
In accordance with this policy, I declare that I have NO past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith.
Mike Beck, DDS, MA
