NS-11 Unraveling the Immunologic Puzzle: Exploring the Impact of Immunology on Apical Periodontitis
CE Hours: 1.5
Description: Apical periodontitis (AP) is a complex inflammatory disease with different clinical and radiographic presentations. The pathogenesis of AP involves an interplay of the innate and adaptive immune responses, that aim at preventing root canal microflora from causing spreading systemic infection and/or osteomyelitis. This session will discuss the major pathways involved in the progression and healing of AP. It will also address the way a myriad of systemic factors may affect this apical immune response.
Learning Objectives:
- Discuss the major immunological pathways involved in the pathogenesis of AP
- Discuss the major immunological mechanisms of healing and bone regeneration following endodontic treatment
- Discuss the potential role of systemic factors in mediating pathogenesis or healing of AP
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LockedAshraf F. Fouad, D.D.S., M.S.
Dr. Fouad obtained his DDS, Certificate of Endodontics, and MS at the University of Iowa.
He served on the faculty and in various administrative roles at the University of Connecticut, the University of Maryland, and the University of North Carolina at Chapel Hill. He is currently Professor and Chair, Department of Endodontics, Director, Advanced Endodontics Program, and Interim Director, Health Information and Business Systems (HIBS) at the University of Alabama at Birmingham.
Dr. Fouad has published over 120 peer-reviewed manuscripts, 62 editorials and invited manuscripts, 25 textbook chapters, and over 150 abstracts. He edited and co-authored several editions of the textbooks: Endodontic Microbiology and Endodontics: Principles and Practice. He served as Associate Editor of the Journal of Endodontics for 15 years and is currently Associate Editor of Dental Traumatology and the Endodontics Section of Frontiers of Dental Medicine. He is a Diplomate and Past President of the American Board of Endodontics. He received the Distinguished Scientist Award from the Pulp Biology and Regeneration Group of the IADR in 2017, the AAE President's Award in 2022, and the International Grossman's Award in 2023.
Disclosure(s): No financial relationships to disclose
Elisabetta Cotti, D.D.S., M.S.
Elisabetta Cotti, DDS, MS, received her DDS from the University of Cagliari – Italy and the specialty and MS in Endodontics from the University of Loma Linda- California.
She is Full Professor of Conservative Dentistry and Endodontics, and the Chairman of the Department of Conservative Dentistry and Endodontics at the School of Dentistry, University of Cagliari- Italy. She is currently the Director of the Post Graduate programme (Master) in Clinical Endodontics at the University of Cagliari, lecturer in the Department of Endodontics at Loma Linda University, USA. She is the president of IFEA (International federation of Endodontic Associations). She practices limited to Endodontics, and is author of several articles and chapters in the field of Endodontics with has a specific interest in apical periodontitis, imaging and trauma.
Disclosure(s): Dentsply Sirona Endodontic SBU: Honorarium (Ongoing), serve as consultant in products development and as lectures (Ongoing)