SP-1 A New Direction in Managing Avulsed Teeth: De novo PDL Regeneration
CE Hours: 0.75
Description:
Managing avulsed teeth is challenging for clinicians, often leading to replacement resorption and unfavorable outcomes. The primary reason is the damage to periodontal ligament cells, and bone cells often invade the root surface rather than slow-moving periodontal ligament (PDL) cells. This leads to ankylosis, and currently, no treatment is available to prevent it.
This presentation will i) discuss the limitations of current management protocols for avulsed teeth; ii) overview recent research on cell-based therapy for PDL regeneration in small, large animal models and clinical trials; and iii) identify the challenges of de novo regeneration of PDL on denuded root using a mini-swine model. This session will provide an understanding of the future direction to establish a new clinical protocol to manage avulsed teeth based on the current progress of cell-based PDL regeneration.
Learning Objectives:
- To discuss the limitations of current management protocols for avulsed teeth
- To overview cell-based therapy for periodontal ligament (PDL) regeneration animal models and clinical trials on humans
- To describe the challenges of PDL regeneration on denuded root in a mini-swine model and discuss a new clinical protocol for clinical management
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Hacer Aksel, DDS, PhD
I am a Clinical Assistant Professor at University at Buffalo since 2018. I completed my Ph.D. at Hacettepe University in Turkey and the University of Tennessee Health Science Center, Department of Bioscience Research in the USA. I completed a specialty training in Endodontics at Hacettepe University in 2016. My research focuses on the regenerative endodontics where we want to achieve predictable tissue regeneration in the root canals for the treatment of necrotic immature permanent teeth. I have research and mentoring experience as a Principle investigator. I have currently 40 published articles in prestigious and respected journals including Tissue Engineering, Journal of Endodontics and International Endodontic Journal. I am Associate Editor of the Turkish Endodontic Journal. My research has been granted by American Association of Endodontics Research Foundation. I have reviewed articles for Peer-reviewed Journals including endodontics, tissue regeneration and biomaterials. I am also a Eureka Expert for the evaluations of Eurostars Projects.
Speaker Disclosure
I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.
