SP-38 The Role of Inflammation Modulation in Vital Pulp Treatments: Bridging Theory and Clinical Practice
CE Hours: 0.75
Description: Vital pulp therapy (VPT) is a treatment approach aimed at preserving the function and health of the dental pulp. While inflammation of the dental pulp marks the beginning of an eventual necrosis, it is also the prerequisite for homeostasis return and regenerative events. One of the key factors affecting the success of VPT is the management of inflammation. In recent years, there has been growing interest in the use of inflammation modulation techniques to improve the outcome of VPT. In this lecture, we discuss the theoretical basis and clinical applications of inflammation modulation in VPT, focusing on the use of anti-inflammatory agents and biomaterials that promote pulp healing and regeneration. The available evidence on the efficacy and safety of these approaches and the challenges and opportunities for their translation into clinical practice will be discussed. Inflammation modulation represents a promising strategy for bridging the gap between theory and clinical practice in VPT and has the potential to improve the long-term outcome and prognosis of this crucial treatment modality.
Learning Objectives:
- Describe the theoretical basis and mechanisms of action of inflammation modulation techniques in vital pulp therapy.
- Evaluate the potential benefits and risks of inflammation modulation techniques in the clinical management of vital pulp therapy
- Apply the knowledge gained from the lecture to identify and design appropriate inflammation modulation strategies in different clinical scenarios of vital pulp therapy.
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Alexis Gaudin, Ph.D, DDS
Pr. Alexis Gaudin, born in 1979, is a full-time professor in the Department of Restorative Dentistry and Endodontics and currently holds the position of 1st Vice-Dean at the dental school "Faculté d'Odontologie de Nantes" within Nantes Université. In 2018, he became a part of the INSERM 1229 RMeS (Regenerative Medicine and Skeleton) research laboratory. His journey in the field began with the completion of his DDS degree from the University of Toulouse, France, in 2002. Subsequently, in December 2015, he obtained his PhD in basic and clinical dental sciences, specializing in the regulation of immune response in the dental pulp, from the University of Nantes, France.
Following his PhD, Dr. Gaudin pursued further expertise by undertaking a one-year postdoctoral program at the University of the Pacific (San Francisco, CA, USA), focusing on pulpal biology and dental stem cells. Upon his return to Nantes, he took the initiative to establish the research group INFLAMED (INFlammatory MEDiators in Bone and Teeth), with the primary objective of connecting fundamental research with clinical practice. Within this group, he provided guidance and supervision to doctoral students engaged in diverse subjects, including dental materials and pulp biology, conducting research in both laboratory and clinical environments.
Dr. Gaudin's contributions to the field are well-recognized, evident through his authorship of numerous articles published in esteemed journals and his involvement in several book chapters on endodontics. Moreover, he has received multiple scientific awards in recognition of his work. He serves as the President of the French Society of Endodontics and is a certified member of the European Society for Endodontics.
Disclosure(s): No financial relationships to disclose