SP-53 Scaffolds for Regenerative Endodontics: Translation of Research into Clinical Practice

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Course Description: 

The goal of regenerative endodontic therapy is to restore the functional integrity of the pulp-dentin complex by applying a combination of biomaterial scaffolds, cells, and biological molecules. As one of the key components in tissue engineering, biomaterial scaffolds provide the structural framework for the regeneration of the pulp-dentin complex. New biological scaffolds functionalized with biological cues such as growth factors and dentin matrix molecules have been designed and investigated to direct a myriad of cellular activities toward pulp regeneration. This lecture will systematically review the properties and biological performance of biomaterial scaffolds utilized in clinical trials and animal studies. Additionally, the histological outcomes of regenerative endodontic treatment in animal models using different scaffolds will be presented based on the findings from the author’s laboratory. The potential application of biological scaffolds for clinical regenerative endodontic therapy will also be discussed for practitioners.

At the conclusion, participants should be able to:

  • Describe the significance of regenerating the pulp-dentin complex.
  • Describe the characteristics and biological performance of biomaterial scaffolds for pulp regeneration.
  • Discuss the potential application of biological scaffolds for clinical regenerative endodontic treatment.


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7 Questions

Sahng Gyoon Kim, D.D.S., M.S.

Dr. Kim earned his D.D.S. degrees at Seoul National University and Columbia University. He received a Certificate in Endodontics and an M.S. in Oral Biology from the University of Pennsylvania. Dr. Kim has received government and private research grants for his research on dental pulp regeneration. He has served on the AAE Research and Scientific Affairs Committee. Dr. Kim has published extensively in the field of dental tissue engineering and has lectured nationally and internationally on dental pulp regeneration. Dr. Kim is a Diplomate of the American Board of Endodontics and an Associate Professor and the Director of Postdoctoral Endodontics Program at Columbia University College of Dental Medicine.

Sahng Gyoon Kim, D.D.S., M.S.

I declare I have a past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith, as indicated: Snoasis: Grant/Research Support