SP-60 Preliminary Analysis of Microbiological Data in a Clinical Trial of Regenerative Endodontic Treatment

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Course Description: 

Residual bacteria have been shown to influence regenerative endodontic treatment (RET) in animal models. Recently, a multi-centered clinical trial of RET was funded by the Foundation for Endodontics, and conducted in four dental schools. Microbiological samples at different stages of treatment were obtained from all patients, and analyzed using contemporary molecular methods. This presentation will address the preliminary microbiological findings in immature teeth with pulp necrosis, the effectiveness of various clinical disinfection and medication protocols, and the differences in microbiological findings in cases with and without clinical success of treatment.

At the conclusion, participants should be able to:

  • Provide current recommendations for disinfection protocols in RET.
  • Explain about contemporary microbiological analyses of complex microbiota of the necrotic pulp in immature teeth.
  • Describe the association of residual bacteria and preliminary outcome of RET.

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Evaluation
7 Questions
Quiz
5 Questions  |  Unlimited attempts  |  4/5 points to pass
5 Questions  |  Unlimited attempts  |  4/5 points to pass

Ashraf F. Fouad, D.D.S., M.S.

Dr. Fouad obtained his DDS, Certificate of Endodontics and MS at the University of Iowa. 

He served on the faculty and in various administrative roles at University of Connecticut, the University of Maryland, and the University of North Carolina at Chapel Hill. He is currently Professor and Chair, Department of Endodontics, Director, Advanced Endodontics Program, and Interim Director, Health Information and Business Systems (HIBS) at the University of Alabama at Birmingham.

Dr. Fouad has published over 110 peer-reviewed manuscripts, 25 textbook chapters, and 145 abstracts. He edited and co-authored the textbooks: Endodontic Microbiology (now in its second edition), as well as the fifth and sixth editions of Endodontics: Principles and Practice. He is a Diplomate and Past President of the American Board of Endodontics, and an Associate Editor of the Journal of Endodontics, Dental Traumatology and Frontiers of Dental Medicine – Endodontics. He received the Distinguished Scientist Award from the Pulp Biology and Regeneration Group of the International Association of Dental Research in 2017, and the AAE President’s Award in 2022.

Speaker Disclosure

I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation

Mahmoud Torabinejad, D.M.D., M.S.D., Ph.D.

Dr. Torabinejad is president and director of the Endodontic Institute of Surgical Education and Research Venues in Irvine. He is a professor of endodontics and former Director of the advanced specialty education program in endodontics at Loma Linda University (LLU) School of Dentistry. Currently, he is professor of endodontics at LLU, research professor at the University of Minnesota, Dean's professor of endodontics at the University of Maryland, affiliate professor of endodontics at the University of Washington in Seattle and adjunct professor of endodontics at the University of Pacific in San Francisco and University of California in San Francisco. He has authored eight textbooks and more than 350 publications. He is the #1 author of citations in classic articles in the field of endodontics and # 1 author of citation for pulp regeneration. He has presented over 250 lectures nationally and internationally in over 40 countries. He received several awards from LLU during his 42-year tenure at LLU. They include: the LLU Centennial Van Guard Award for Healing, the Distinguished Research Award from the Dental School, and the LLU distinguished investigator award. He is the recipient of the Louis I. Grossman Award of the French Association of Endodontists. He has received the Ralph F. Sommer Award of the American Association of Endodontists (AAE) twice, Louis I. Grossman Award of the AAE, Philanthropic award of the Foundation for Endodontics, the Edgar D. Coolidge Award of the AAE. He is a past president of the California Association of endodontics and past president of the AAE and its Foundation.

Anibal R. Diogenes, D.D.S., M.S., Ph.D.

Dr. Anibal Diogenes received his D.D.S. from UFPE in Brazil, his M.S. in Molecular Biology from the University of Nebraska, and his Ph.D. in Pharmacology and Certificate in Endodontics from the University of Texas Health Science Center at San Antonio. Dr. Diogenes is the Vice-Chair of the department of Endodontics at the University of Texas Health at San Antonio, and a director of the American Board of Endodontics. His areas of research include, inflammation, pain and regenerative endodontics. 

Speaker Disclosure

I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation

Ashraf F. Fouad, D.D.S., M.S.
I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

Anibal Diogenes, D.D.S., M.S., Ph.D.
I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

Mahmoud Torabinejad, D.MD, M.S.D., PhD
I declare I have a past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith, as indicated:Dentsply International (Self) : Grant/Research Support (Status: Terminated --- July 1, 2017)