
Unraveling the Etiology and Pathogenesis of Multiple Cervical Root Resorption – A Scoping Review
CE Hours: 1.0
Description: Multiple Cervical Root Resorption (MCRR) is a rare condition characterized by the progressive destruction of the cervical region of multiple tooth roots, leading to significant tooth loss. The etiology and pathogenesis of MCRR remain poorly understood. Existing knowledge is largely derived from case reports/series. A comprehensive review of literature is crucial to identify potential systemic and dental factors that contribute to the development and progression of MCRR.
At the conclusion of this article, the reader will be able to:
- Describe the systemic diseases, genetic mutations, and medications that have been implicated in multiple cervical root resorption.
- Discuss the common pathogenic pathways shared by multiple cervical root resorption and conditions affecting the skeletal system.
- Describe the role of interdisciplinary collaboration in the diagnosis and management of multiple cervical root resorption.
Key:






Yuhong Lin, DDS
Dr. Yuhong Lin is a second year Endodontics resident at Texas A&M University College of Dentistry. She received her dental degree from UTHealth Houston School Dentistry.

Vivek Thumbigere-Math, BDS, PhD
Vivek Thumbigere Math, BDS, PhD, is a board-certified periodontist and Assistant Professor in the Division of Periodontics at the University of Maryland School of Dentistry. He is nationally an internationally recognized for his leadership in periodontology, combining excellence in clinical care, education, and translational research to improve oral and systemic health outcomes. Dr. Math earned his Bachelor of Dental Surgery (BDS) in India, followed by a PhD and residency training in Periodontology at the University of Minnesota. He subsequently completed a prestigious postdoctoral fellowship at the National Institutes of Health (NIH) under the mentorship of Dr. Martha Somerman (former director of NIDCR). At the University of Maryland, Dr. Math provides advanced periodontal and implant care with a strong emphasis on evidence-based, patient-centered treatment. As a passionate educator, Dr. Math mentors dental students and periodontology residents while actively contributing to curriculum development and innovation. His research focuses on periodontal disease pathogenesis, osteoimmunology, and the intersection between oral and systemic diseases. His research program has been continuously supported by competitive NIH funding. He has authored over 40 peer-reviewed publications in leading scientific journals and is a frequently invited speaker at national and international conferences. Dr. Math serves on multiple NIH study sections and editorial boards, and is currently Associate Editor of Frontiers in Dental Medicine.

Anil Kishen, B.D.S., M.D.S., Ph.D.
Dr. Anil Kishen is the Dean, Zwingenberger Decanal Chair, and Professor ofEndodontics at the Faculty of Dentistry, University of Toronto. He also holds aTier 1 Canada Research Chair in Oral Health Nanomedicine.
Dr. Kishen has received numerous honors, including the 2020Louis I. Grossman Award from the American Association of Endodontists, the 2023National Dental Research Award (CADR/ACFD), the W. W. Wood Award for excellencein dental education, and the Enterprise Challenge Innovator Award in Singapore.
He has published over 300 journal articles, 24 bookchapters, and three books, and holds 12 patents. He has delivered more than 200invited lectures globally and serves as Associate Editor for several leadingjournals, including the Journal of Endodontics.
His research, funded by federal and foundation grants,focuses on wound healing, nanoparticle-guided tissue engineering, andmicrobe–host cell interactions.

Jianing He, D.M.D., Ph.D.
Dr. Jianing (Jenny) He received her dental degree from West China University of Medical Sciences in 1996, and a certificate in Endodontics and a PhD in Oral Biology from the University of Connecticut Health Center in 2003.
Dr. He has been actively involved in endodontic education, research, and clinical practice. She is a Diplomate of the American Board of Endodontics, and a fellow of American College of Dentists. She has published over 50 manuscripts in peer-reviewed journals and co-authored chapters in 4 textbooks including Pathways of the Pulp. Dr. He served on the Regenerative Endodontics committee, Research and Scientific Affairs committee for the AAE, and she is currently an Associate Editor of the Journal of Endodontics.
Dr. He is an Adjunct Professor at Texas A&M University College of Dentistry, and maintains a full-time private practice limited to Endodontics in McKinney and Flower Mound, Texas.
Speaker Disclosure
In accordance with this policy, I declare I have a past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith, as indicated: Brasseler USA (Individual(s) Involved: Self): Honorarium (Terminated)