Speakers: Ashraf F. Fouad, D.D.S., M.S.;Anibal Diogenes, D.D.S., M.S., Ph.D.; Mahmoud Torabinejad, D.MD, M.S.D., PhD| This presentation will address the preliminary microbiological findings in immature teeth with pulp necrosis, the effectiveness of various clinical disinfection and medication protocols, and the differences in microbiological findings in cases with and without clinical success of treatment.​

Speakers: Anil Chandra, MDS| Normal human impacted third molars were collected from adults (19–29 years of age). The crowns of immature human premolars extracted for orthodontic reasons in 12- to 14- year old patients were sectioned, the dental pulps were carefully removed without touching the predentin.

Speaker: Avina Paranjpe, B.D.S., M.S.D., M.S., Ph.D.|This is important to understand as the success of REPs depends on SCAP survival and ability to differentiation among other factors. Hence, it is imperative to identify compounds that can help SCAP differentiate thereby helping our regenerative procedures. N-acetyl cysteine (NAC) is an effective anti-oxidant and differentiation agent. SCAP in combination with NAC has shown promising results helping these cells to survive and differentiate. This differentiation could possibly increase the success rates of REPs.​

Speaker: Su-Min Lee, D.D.S., M.S., D.S.cD.|This presentation will review the perspectives in disinfection protocols for regenerative endodontic procedures.

Speakers: Anibal Diogenes, D.D.S., M.S., Ph.D., Avina Paranjpe, B.D.S., M.S.D., M.S., Ph.D. and Domenico Ricucci, D.D.S., MD | Regenerative endodontic procedures aim to form a vital tissue into an empty but infected root canal space that restores the lost functions of the native dental pulp. These procedures have been shown to promote healing of apical periodontitis and further root development by the deposition of hard tissue and continued root development in immature permanent teeth with necrotic pulp and apical periodontitis/abscess.

Speakers: George Huang and Adham A. Azim| It has been long recognized that the key to endodontic success is largely determined by how well the root canal system is disinfected. To render the canal bacteria-free is challenging. Mechanical debridement alone is limited in reaching all the root canal spaces.

Speaker: Jerome J. Cymerman, D.M.D.| This presentation will describe an enhanced revision of endodontic regenerative therapy to treat non-vital or previously treated open apex teeth. This incorporates the addition of a bovine collagen-carbonate apatite scaffold to the currently established regenerative endodontic technique.

Speaker: George Huang, D.D.S., M.S.D., D.Sc.| This presentation attempts to provide updated knowledge on the current understanding of dental pulp stem cells, oral stem cells and the ongoing research.

Speaker: Sahng Gyoon Kim, D.D.S., M.S.| This lecture will systematically review the properties and biological performance of biomaterial scaffolds utilized in clinical trials and animal studies. Additionally, the histological outcomes of regenerative endodontic treatment in animal models using different scaffolds will be presented based on the findings from the author’s laboratory. The potential application of biological scaffolds for clinical regenerative endodontic therapy will also be discussed for practitioners.​

Speaker: Amir Azarpazhooh, D.D.S., M.Sc., PhD, FRCD(C). Because of the limitations of conventional radiography, the application of high-resolution cone beam computed tomography (CBCT) imaging in detecting VRF has generated considerable interest. The purpose of this presentation is to critically appraise the best clinical research available to demonstrate the diagnostic ability of CBCT in detecting VRFs in endodontically treated teeth.