Regenerative Endodontics

Regenerative Endodontics

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  • Product not yet rated Includes Credits

    CE Hours: 0.75

    Description:

    Managing avulsed teeth is challenging for clinicians, often leading to replacement resorption and unfavorable outcomes. The primary reason is the damage to periodontal ligament cells, and bone cells often invade the root surface rather than slow-moving periodontal ligament (PDL) cells. This leads to ankylosis, and currently, no treatment is available to prevent it. 

    This presentation will i) discuss the limitations of current management protocols for avulsed teeth; ii) overview recent research on cell-based therapy for PDL regeneration in small, large animal models and clinical trials; and iii) identify the challenges of de novo regeneration of PDL on denuded root using a mini-swine model. This session will provide an understanding of the future direction to establish a new clinical protocol to manage avulsed teeth based on the current progress of cell-based PDL regeneration.

    Learning Objectives:  

    • To discuss the limitations of current management protocols for avulsed teeth
    • To overview cell-based therapy for periodontal ligament (PDL) regeneration animal models and clinical trials on humans
    • To describe the challenges of PDL regeneration on denuded root in a mini-swine model and discuss a new clinical protocol for clinical management

    Hacer Aksel, DDS, PhD

    I am a Clinical Assistant Professor at University at Buffalo since 2018. I completed my Ph.D. at Hacettepe University in Turkey and the University of Tennessee Health Science Center, Department of Bioscience Research in the USA. I completed a specialty training in Endodontics at Hacettepe University in 2016. My research focuses on the regenerative endodontics where we want to achieve predictable tissue regeneration in the root canals for the treatment of necrotic immature permanent teeth. I have research and mentoring experience as a Principle investigator. I have currently 40 published articles in prestigious and respected journals including Tissue Engineering, Journal of Endodontics and International Endodontic Journal. I am Associate Editor of the Turkish Endodontic Journal. My research has been granted by American Association of Endodontics Research Foundation. I have reviewed articles for Peer-reviewed Journals including endodontics, tissue regeneration and biomaterials. I am also a Eureka Expert for the evaluations of Eurostars Projects.

    Speaker Disclosure

    I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

  • Includes Credits

    CE Hours: 2.0

    Description: Regenerative endodontics represents a paradigm shift in endodontics that has the primary goal of preservation or reestablishment of homeostatic physiological pulp functions. An inflamed dental pulp has been thought to be incapable of healing. This dogma is even reflected in the diagnostic term: “irreversible pulpitis”. Also, pulp necrosis has been a condition that required root canal spaces to be filled with inert materials to prevent growth of microorganisms. Unfortunately, obturation also prevents the growth of patients own living tissues that could bring back important physiological functions lost due to partial or total pulp necrosis. Advancements in biological understanding, techniques and materials have made regenerative endodontic procedures (vital pulp therapies and revitalization) alternatives to teeth requiring non-surgical endodontic treatment. In this lecture, the application of regenerative endodontic approaches will be discussed in light of real clinical scenarios, presenting the advantages and disadvantages of these procedures and their possible pitfalls while contrasting with what is well-known in more “traditional” non-surgical endodontic therapies.

    Learning Objectives: 

    • Identify the prognostic factors for pulp revitalization and pulpotomies
    • Understand the expected outcomes of pulp revitalization and vital pulp therapies
    • List the most common pitfalls with revitalization and pulpotomies and how to avoid them

    Anibal R. Diogenes, D.D.S., M.S., Ph.D.

    Dr. Anibal Diogenes received his D.D.S. from UFPE in Brazil, his M.S. in Molecular Biology from the University of Nebraska, and his Ph.D. in Pharmacology and Certificate in Endodontics from the University of Texas Health Science Center at San Antonio. Dr. Diogenes is the Vice-Chair of the department of Endodontics at the University of Texas Health at San Antonio, and a director of the American Board of Endodontics. His areas of research include, inflammation, pain and regenerative endodontics. 

    Speaker Disclosure

    I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation

  • Product not yet rated Includes Credits

    CE Hours: 0

    Description: How do you decide what technology advancements and techniques to implement into your endodontic practice? As with any development, the body of evidence, technical skill and innovation continues to mature within the profession. With this development also comes questions regarding clinical efficacy and safety, protocols and optimization and evidence-based outcomes. This lecture will offer perspectives from both seasoned endodontists: Dr. Kirk Coury and Dr. Jim Smith (~70 years combined experience) as well as Newer Endodontists: Dr. Anthony Mo and Dr. Michael Adams (~8 years combined experience) as to what was important in their decision-making process, learning curves, and clinical results.

    • Discuss a historical progression of evaluating and incorporating new technology into a modern endodontic practice.
    • Describe the rationale and benefits for implementing technological advancements and techniques into a practice
    • Outline a variety of clinical perspectives and tips for integration and optimization to enhance clinical protocols and outcomes


    Kirk A. Coury D.D.S., M.S.

    Dr. Kirk A. Coury is a graduate of Baylor College of Dentistry, and attended the University of Texas, Houston where he received his Certificate in Endodontics and Master’s Degree in Dentistry in 1990. Dr. Coury is an active member of the American Association of Endodontists, the Foundation for Endodontics, is a Diplomate of the American Board of Endodontics and is a Fellow of the American and International Colleges of Dentists, and is a founding partner in U.S. Endo Partners. Dr. Coury maintains a full-time practice in Amarillo, Texas since 1990. When not saving teeth and making patients’ lives better with endodontic treatment, he has a passion for chasing wild trout, cooking, and exploring fine wine, bourbon and tequila.

    Speaker Disclosure 

    In accordance with this policy, I declare I have a past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith, as indicated: DENTSPLY Tulsa Dental Specialties (Individual(s) Involved: Self):  Key Opinion Leader; Sonendo Inc. (Individual(s) Involved: Self): Consultant, Honorarium, Key Opinion Leader

    James A. Smith, DMD

    Dr. Smith received his dental degree in 1980 from The University of Alabama School of Dentistry and completed his endodontic residency there in 1982.He has been in private endodontic practice for over 39 years and is a retired adjunct assistant professor with the Department of Endodontics at The University of Alabama at Birmingham School of Dentistry. Dr. Smith has co-authored an article that was published in the November 2014 Journal of Endodontics. His practice is located in Birmingham, Alabama.

    Speaker Disclosure 

    In accordance with this policy, I declare I have a past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith, as indicated: Sonendo Inc. (Individual(s) Involved: Self): KOL and Scientific Advisory Board Member with Sonendo Inc., Other Financial or Material Support

    Michael D. Adams, DDS, MDS

    Dr. Adams is a graduate of the University of Nebraska Medical College of Dentistry, earning his DDS in 2017. After working for a year as a general dentist he completed his endodontic residency at the University of Tennessee Health Science Center in Memphis in 2020 where he earned his specialist certificate in endodontics as well as a Master of Dental Science degree. Dr. Adams finds great satisfaction in helping patients save their natural teeth while utilizing the latest endodontic technology. He currently practices with Dr. James A. Smith Jr. at Advanced Endodontics in Birmingham, AL.

    Speaker Disclosure 

    I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

    Anthony Mo, BSc DMD MSc

    Dr. Mo grew up in Alberta where he completed a Bachelor of Science degree in Biochemistry (1996). After volunteering in a church service mission in Australia for two years, he met his now wife and settled in Sydney down under. Following in his father's footsteps, he pursued a career in Dentistry and graduated with honours from renowned Sydney University (2006). Dr. Mo worked and ran a successful practice in the heart of the financial district in Sydney for 8 years until he decided to renew his Canadian roots and pursue his passion for Endodontics at UBC. Recently completing a Master of Craniofacial Science and Diploma in Endodontics and earning Fellowship with the Royal College of Dentists of Canada. Dr. Mo is passionate about education and advances in the field of dentistry. He actively engages in continuing education both as a teacher and a student in endodontics. His other interests include cosmetic and biomimetic dentistry as well as implant dentistry, in which he holds a certificate from UCLA (2010).

    Speaker Disclosure 

    In accordance with this policy, I declare I have a past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith, as indicated: Sonendo Inc. (Individual(s) Involved: Self): Consultant, Honorarium

  • Product not yet rated Includes Credits

    CE Hours: 1.0

    Description: This multicentered cohort study evaluated factors associated with patient-centered outcomes of immature permanent teeth that received regenerative endodontic procedures (REPs) or apexification treatment (APEX).ne modulation in AP and a comprehensive review of the immunomodulatory effect of antimicrobial intracanal medications applied in endodontics with specific emphasis on the antimicrobial nanomaterial-based approaches that provide immunomodulatory potential for successful clinical deployment in endodontics. (J Endod 2022;48:430–456.)

    • Describe the success rates of regenerative endodontic procedures (REPs) and apexification treatment (APEX).
    • Explain the possible predictors that affect outcome of REPs and APEX. 
    • Describe the potential treatment steps that may lower the failure rate of teeth receiving REP and APEX.


    Sharon M. Casey

    Sharon M. Casey

      AffiliationsBoston University School of Public Health, Boston, Massachusetts

      Department of Endodontics, New York University College of Dentistry, New York, New York

      Dani Fox

      Wilson Duong, D.D.S.

      Natasha M.. Flake, D.D.S., Ph.D., M.S.D.

      Natasha M. Flake, DDS, PhD, MSD is an Associate Professor and the Director of Predoctoral Endodontics in the Department of Endodontics at the University of Washington School of Dentistry. She is Director of the Endodontic Clerkship and Chair of the Clerkship Directors Committee at the School of Dentistry, where she holds the Robert J. Oswald and David L. Pitts Endowed Professorship in Endodontics. Dr. Flake earned a BS in Biological Sciences from the University of Missouri, a DDS and PhD in neuroscience from the University of Maryland, and an MSD and Certificate in Endodontics from the University of Washington. Her research interests include the mechanisms of nociception, pain, and analgesia, as well as regenerative endodontic outcomes. Dr. Flake is the 2016 recipient of the Edward M. Osetek Educator Award, and she currently serves on the Board of Directors of the AAE. Dr. Flake is a Diplomate of the American Board of Endodontics, and she practices endodontics one day per week in private practice in Seattle, Washington.

      Asma A. Khan, BDS, Phd

      Dr Asma Khan is a tenured Associate Professor at the University of North Carolina- Chapel Hill. After dental school, Dr Khan completed her PhD in Neuroscience from the University of Maryland and a fellowship in clinical pain research at the NIH. She then moved to University of Texas at San Antonio where she earned a certificate in Endodontics and completed a post-Doctoral fellowship. Her areas of research include Orofacial Pain and Regenerative Endodontics.

      Jennifer L. Gibbs, MS, DDS, PhD

      Jennifer L. Gibbs, M.A.S, D.D.S., Ph.D. is Director of the Endodontics Division and Program Director of Advanced Graduate Education Program in Endodontics and an Associate Professor at Harvard School of Dental Medicine

      Dr. Gibbs received her dental degree and her Ph.D. in Pharmacology from the University of Texas Health Science Center San Antonio. She then completed a certificate in Endodontics and an M.A.S. in Clinical Research from the University of California San Francisco, as well as a postdoctoral training period. She is now a full time faculty at Harvard.

      Dr. Gibbs heads a translational research group focused on understanding the neurobiological mechanisms of orofacial pain with a focus on dental pain, and patient centered outcomes of endodontic treatments. She teaches clinically in the advanced graduate Endodontic Program and lectures to both post-graduate and pre-doctoral students. Dr. Gibbs cares for patients at the Faculty Practice at Harvard. She is a past Educator Fellow of the American Association of Endodontics.

      Disclosure

      In accordance with this policy, I declare that I have NO past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith.

    • Includes Credits

      CE Hours: 1.0

      Description: Endodontic management of immature permanent teeth with pulpal necrosis is challenging. Regenerative endodontic treatments have been suggested as a treatment modality so that the affected teeth continue with the root development and hard tissue deposition on the dentinal wall and are preserved as long as possible for our young patients. Yet, several variables may affect the outcome of regenerative endodontic treatments. This presentation aims to comprehensively review the advances in foundational research in regenerative endodontics and their impact on clinical protocols and the outcomes of regenerative endodontic treatments. In this presentation, we will critically review two areas: i) We will discuss the recent endeavor on hydrogel scaffolds and biocompatible synthetic materials for regenerative endodontics. The potential application of these advances will also be discussed for practitioners. ii) We will discuss the predictability of clinical success in teeth treated by regenerative endodontics.

        Discuss current research related to regenerative endodontics.
      • Discuss the novel tissue engineering methods in regenerative endodontics
      • List current recommendations for regenerative endodontic treatment protocols and understand the outcomes of clinically treated cases with regenerative endodontic treatments.

      Hengameh Bakhtiar, D.D.S., M.S.c

      Associate professor, Visiting Professor, Faculty of Dentistry, University of Toronto. Endodontic Department, faculty of dentistry, Islamic Azad University, Tehran. Iran. Responsibilities: 1.Academic: *Practical endodontics for undergraduate and postgraduate Students. *Courses on endodontics for undergraduate and postgraduate Students. *lectures in continual retraining courses for dentists. 2. Research interests: *Bioactive Materials in Dentistry and endodontics *Regenerative Endodontics *Regenerative Dentistry *Tissue engineering and Regenerative Medicine in Dentistry Ongoing Research Projects: *Nano fibrous scaffolds containing antibiotics for Regenerative Endodontics *Injectable synthetic scaffolds for Regenerative Endodontics * ECM scaffolds and synthetic in situ forming biomaterials for Regenerative Endodontics

      Hengameh Bakhtiar, D.D.S., M.S.c
      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

    • Includes Credits

      CE Hours: 1.0

      Description:Regenerate Endodontics is the innovative field in Endodontics that seeks to promote a biological root growth to save immature necrotic teeth. Regenerative Endodontic Procedures (REPs) are still being investigated, as multiple individual factors can interfere with the successful outcome. The AAE strongly supports clinicians and researchers to develop new strategies in regenerative endodontics. The Regenerative Endodontic Committee created a web-based survey which was offered to AAE members to share their treatment protocols for immature necrotic teeth. This presentation will offer to the assistants an overview of the data collected from more than 200 participants. 125 complete cases with good quality follow-up images were collected and 69 cases with at least 6 months of follow-up were analyzed. Research based on web data survey is a powerful tool to overcome some of the challenges in clinical research. In this presentation, committee members will discuss the advantages and disadvantages encountered during the collection and analysis of this data. The committee also wants to recognize the survey’s participants for their important contribution to future research in Regenerative Endodontics.

      • List most common protocols used by clinicians in REP in terms of irrigants, instrumentation, intracanal medicaments, materials used, etc.
      • Describe what the most predictable factors are to consider when selecting your patients for a REP.
      • Recognize the importance of the web-based survey to overcome the challenges, such as a significant sample size, to perform a relevant clinical research.

      Jennifer L. Gibbs, MS, DDS, PhD

      Jennifer L. Gibbs, M.A.S, D.D.S., Ph.D. is Director of the Endodontics Division and Program Director of Advanced Graduate Education Program in Endodontics and an Associate Professor at Harvard School of Dental Medicine

      Dr. Gibbs received her dental degree and her Ph.D. in Pharmacology from the University of Texas Health Science Center San Antonio. She then completed a certificate in Endodontics and an M.A.S. in Clinical Research from the University of California San Francisco, as well as a postdoctoral training period. She is now a full time faculty at Harvard.

      Dr. Gibbs heads a translational research group focused on understanding the neurobiological mechanisms of orofacial pain with a focus on dental pain, and patient centered outcomes of endodontic treatments. She teaches clinically in the advanced graduate Endodontic Program and lectures to both post-graduate and pre-doctoral students. Dr. Gibbs cares for patients at the Faculty Practice at Harvard. She is a past Educator Fellow of the American Association of Endodontics.

      Disclosure

      In accordance with this policy, I declare that I have NO past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith.

      Tatiana M. Botero, D.D.S., M.S.

      Dr. Botero received her dental degree (DDS, 1987) from CES University in Medellin, Colombia, Specialty training in Endodontics at Pontificia Universidad Javeriana in Bogotá, Colombia (1995) and the advanced Specialty Certificate in Endodontics from University of Michigan in 2005. She was Clinical Assistant Professor at CES University and had her private practice in Colombia (1989-2000). Dr. Botero joined the University of Michigan in 2001 and presently she is full time Clinical Professor and teaches Endodontics to graduate and undergraduate students. She is the director of the dental postgraduate fellowship program in endodontics. She also practices Endodontics at a private Dental clinic in Michigan. In 2012 Dr. Botero became a Diplomate of the American Board of Endodontics and she joined the Regenerative Endodontic committee from the American Association of Endodontics since 2013 and chair 2014-2020. She is Past-president of the Pulp Biology and Regeneration group of the American Association and International Association of Dental Research. Dr. Botero has authored and co-authored numerous scientific peer reviewed articles and book chapters. She serves as reviewer for several endodontic and dental journals. Her research of interest and publications are on caries-induced angiogenesis and Regenerative Endodontics.

      Speaker Disclosure

      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

      Vanessa Chrepa, D.D.S., M.S.

      Dr. Vanessa Chrepa was born and raised in Athens, Greece. She received her DDS from University of Athens, School of Dentistry and completed her residency and Master’s degree in Endodontics at UT Health San Antonio. She is currently an Associate Professor of Endodontics with tenure at UT Health San Antonio and the predoctoral director for Endodontics. Dr. Chrepa is a Diplomate of the American Board of Endodontics and received the 2017 AAE Educator Fellowship Award. Her research interests include regenerative endodontics, stem cell biology, endodontic outcomes, and cannabinoids for dental pain. She serves as an Editorial Review member for the Journal of Endodontics and International Endodontic Journal among others. Alongside her teaching and research, Dr. Chrepa maintains a private practice limited to Endodontics.

      Jennifer Gibbs, D.D.S., M.S., Ph.D.
      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

      Tatiana Botero, MS
      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation

      Vanessa Chrepa, D.D.S., M.S.
      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.


    • Includes Credits

      CE Hours: 1.5

      Description: Regenerative endodontics represents a paradigm shift with the primary goal of preservation or reestablishment of homeostatic physiological pulp functions. An inflamed dental pulp has been thought to be incapable of healing. This dogma is even reflected in the diagnostic term: “irreversible pulpitis”. Also, pulp necrosis has been a condition that required root canal spaces to be filled with inert materials to prevent growth of microorganisms. Unfortunately, obturation also prevents the growth of patients own living tissues that could bring back important physiological functions lost due to partial or total pulp necrosis. Advancements in biological understanding, techniques and materials have made regenerative endodontic procedures (vital pulp therapies and revitalization) alternatives to teeth requiring non-surgical endodontic treatment. In this lecture, the application of regenerative endodontic approaches will be discussed in light of real clinical scenarios, presenting the advantages and disadvantages of these procedures and their possible pitfalls while contrasting with what is well-known in more “traditional” non-surgical endodontic therapies.

      • Explain what regenerative endodontic procedures are.
      • Recognize the advantages and disadvantages of regenerative endodontic procedures.
      • Discuss and support clinical decisions with evidence, but also consider patients' expectations and restorative needs.

      Anibal R. Diogenes, D.D.S., M.S., Ph.D.

      Dr. Anibal Diogenes received his D.D.S. from UFPE in Brazil, his M.S. in Molecular Biology from the University of Nebraska, and his Ph.D. in Pharmacology and Certificate in Endodontics from the University of Texas Health Science Center at San Antonio. Dr. Diogenes is the Vice-Chair of the department of Endodontics at the University of Texas Health at San Antonio, and a director of the American Board of Endodontics. His areas of research include, inflammation, pain and regenerative endodontics. 

      Speaker Disclosure

      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation

      Anibal Diogenes, D.D.S., PhD

      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.


    • Product not yet rated Includes Credits

      CE Hours: 1.25

      Description: This presentation will clarify the concept of regenerative endodontics and review its progress. There are two categories of clinical approaches to regain vitalization of pulp. One is stem-cell based therapy that involves implanting exogenously processed stem cells into the root canal space, termed cell-based regenerative endodontic therapy (CB-RET). This approach has shown the regeneration of pulp- and dentin-like tissues in the canal space from animal and human clinical trial studies, suggesting potential practice of true “regenerative endodontics” in the future. On the other hand, revitalization or also termed revascularization, that does not involve the delivery of exogenously processed stem cells into the canals therefore is termed cell-free regenerative endodontic therapy (CF-RET). The various animal and human clinical studies have shown that the tissues developed in CF-RETs are fibrous connective tissue, some resembling periodontal ligament, not pulp-like, and the mineral tissue as cementum-like or bone, not dentin-like. One outcome regarding revitalization treatment is canal space obliteration by calcification which accounts for a high percentage of such cases. 

      • Describe the definitions of CB-RET and CF-RET.
      • Describe the progress of CB-RET.
      • Describe the progress of CF-RET. 

      George T-J. Huang, D.D.S., M.S.D., D.Sc

      Dr. Huang is a board-certified endodontist, currently Professor and former Director for Stem Cells and Regenerative Therapies, Department of Bioscience Research at UTHSC, College of Dentistry. He is the former Chair/Herbert Schilder Professor in Endodontics, at Boston University, also a former Chair in Endodontics at Columbia University.  Dr. Huang has published ~180 research articles, abstracts, review articles, including papers in Stem Cells, Stem Cells and Development, Stem Cell Research and Therapy, Stem Cell Reviews and Reports, Tissue Engineering, Regenerative Medicine, Infection and Immunity, Human Gene Therapy, Journal of Dental Research, Journal of Endodontics, etc; and 19 book chapters in books such as Ingle’s Endodontics, Cohen’s Pathways of the Pulp, Endodontic Microbiology, Principles of Regenerative Medicine, Tissue Engineering and Regenerative Dentistry, Tissue-Specific Stem Cell Niche, Material-Tissue Interfacial Phenomena, etc; and co-edited with Dr. Irma Thesleff and wrote chapters for the text book “Stem cells, craniofacial development and regeneration”, in 2013, published by Wiley-Blackwell. He currently an Associate Editor for the journal Stem Cell Research and Therapy. His research has been funded by various sources including NIH and AAE Foundation. His current research interest is in the area of stem cells and regenerative medicine. Distinguished Scientist Award, IADR, 2015.

      George T.-J. Huang, DDS, MSD, DSc

      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.


    • Includes Credits

      CE Hours: 0

      Description: Regenerative endodontic treatment of immature teeth is now advocated as first treatment choice for immature teeth with pulp necrosis. Traditionally, calcium hydroxide apexification and more recently MTA apical barrier techniques are alternative approaches. A disadvantage of these approaches is no further root development and a belief that calcium hydroxide may weaken teeth. The veracity of that claim will be examined. Clinical outcomes regarding resolution of signs and symptoms of infection are similar for all approaches. Immature teeth with pulp necrosis treated with REPs generally show further root maturation although the results are variable. Furthermore, patient-based criteria such as tooth discoloration, indications for changing the treatment option, and number of treatment appointments are all important parameters for discussion before electing the appropriate treatment plan for the management of immature teeth with pulp necrosis. Recommendations for which treatment approach are dependent on aesthetic requirements and stage of root development.

      • Describe the parameters of success in the treatment of immature teeth
      • Evaluate patient and clinician based outcome measures.
      • Evaluate the efficacy of three treatment approaches for immature permanent teeth with pulp necrosis

      Bill Kahler, DClinDent., Ph.D.

      Bill maintains a full time specialist private practice restricted to Endodontics in Brisbane and Toowoomba, Australia. He works in a dedicated trauma clinic for Queensland Health. In addition, Bill holds an honorary Associate Professor title at the University of Queensland. He is a Board member of the International Association of Dental Traumatology and is an author on the ‘IADT Guidelines for management of traumatic dental injuries’. He graduated DClinDent (Endo) from the University of Adelaide and has a PhD from the University of Sydney as well as numerous Fellowships. Bill has published more than 70 papers in international dental, material science and engineering journals. His papers are cited as reference texts by the American Association of Endodontists and the International Association of Dental Traumatology for the treatment of dental trauma and regenerative endodontic procedures. Bill is a contributing author for book chapters on endodontic outcomes and dental trauma, including “Pathways of the Pulp 12 edition” and the “Textbook and Color Atlas of Traumatic Injuries to the Teeth”. He has lectured extensively nationally and internationally and has numerous international research collaborations in every continent.

      Bill Kahler, DClinDent., Ph.D.

      In accordance with this policy, I declare that I have NO past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith.

    • Includes Credits

      CE: 0

      Course Description: 

      Residual bacteria have been shown to influence regenerative endodontic treatment (RET) in animal models. Recently, a multi-centered clinical trial of RET was funded by the Foundation for Endodontics, and conducted in four dental schools. Microbiological samples at different stages of treatment were obtained from all patients, and analyzed using contemporary molecular methods. This presentation will address the preliminary microbiological findings in immature teeth with pulp necrosis, the effectiveness of various clinical disinfection and medication protocols, and the differences in microbiological findings in cases with and without clinical success of treatment.

      At the conclusion, participants should be able to:

      • Provide current recommendations for disinfection protocols in RET.
      • Explain about contemporary microbiological analyses of complex microbiota of the necrotic pulp in immature teeth.
      • Describe the association of residual bacteria and preliminary outcome of RET.

      Ashraf F. Fouad, D.D.S., M.S.

      Dr. Fouad obtained his DDS, Certificate of Endodontics and MS at the University of Iowa. 

      He served on the faculty and in various administrative roles at University of Connecticut, the University of Maryland, and the University of North Carolina at Chapel Hill. He is currently Professor and Chair, Department of Endodontics, Director, Advanced Endodontics Program, and Interim Director, Health Information and Business Systems (HIBS) at the University of Alabama at Birmingham.

      Dr. Fouad has published over 110 peer-reviewed manuscripts, 25 textbook chapters, and 145 abstracts. He edited and co-authored the textbooks: Endodontic Microbiology (now in its second edition), as well as the fifth and sixth editions of Endodontics: Principles and Practice. He is a Diplomate and Past President of the American Board of Endodontics, and an Associate Editor of the Journal of Endodontics, Dental Traumatology and Frontiers of Dental Medicine – Endodontics. He received the Distinguished Scientist Award from the Pulp Biology and Regeneration Group of the International Association of Dental Research in 2017, and the AAE President’s Award in 2022.

      Speaker Disclosure

      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation

      Mahmoud Torabinejad, D.M.D., M.S.D., Ph.D.

      Dr. Torabinejad is president and director of the Endodontic Institute of Surgical Education and Research Venues in Irvine. He is a professor of endodontics and former Director of the advanced specialty education program in endodontics at Loma Linda University (LLU) School of Dentistry. Currently, he is professor of endodontics at LLU, research professor at the University of Minnesota, Dean's professor of endodontics at the University of Maryland, affiliate professor of endodontics at the University of Washington in Seattle and adjunct professor of endodontics at the University of Pacific in San Francisco and University of California in San Francisco. He has authored eight textbooks and more than 350 publications. He is the #1 author of citations in classic articles in the field of endodontics and # 1 author of citation for pulp regeneration. He has presented over 250 lectures nationally and internationally in over 40 countries. He received several awards from LLU during his 42-year tenure at LLU. They include: the LLU Centennial Van Guard Award for Healing, the Distinguished Research Award from the Dental School, and the LLU distinguished investigator award. He is the recipient of the Louis I. Grossman Award of the French Association of Endodontists. He has received the Ralph F. Sommer Award of the American Association of Endodontists (AAE) twice, Louis I. Grossman Award of the AAE, Philanthropic award of the Foundation for Endodontics, the Edgar D. Coolidge Award of the AAE. He is a past president of the California Association of endodontics and past president of the AAE and its Foundation.

      Anibal R. Diogenes, D.D.S., M.S., Ph.D.

      Dr. Anibal Diogenes received his D.D.S. from UFPE in Brazil, his M.S. in Molecular Biology from the University of Nebraska, and his Ph.D. in Pharmacology and Certificate in Endodontics from the University of Texas Health Science Center at San Antonio. Dr. Diogenes is the Vice-Chair of the department of Endodontics at the University of Texas Health at San Antonio, and a director of the American Board of Endodontics. His areas of research include, inflammation, pain and regenerative endodontics. 

      Speaker Disclosure

      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation

      Ashraf F. Fouad, D.D.S., M.S.
      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

      Anibal Diogenes, D.D.S., M.S., Ph.D.
      I declare that I have no proprietary, financial, or other personal interest of any nature or kind in any product, service, course, and/or company, or in any firm beneficially associated therewith, that will be discussed or considered during the proposed presentation.

      Mahmoud Torabinejad, D.MD, M.S.D., PhD
      I declare I have a past or present proprietary or relevant financial relationship or receive gifts in kind (including soft intangible remuneration), consulting position or affiliation, or other personal interest of any nature or kind in any product, service, course and/or company, or in any firm beneficially associated therewith, as indicated:Dentsply International (Self) : Grant/Research Support (Status: Terminated --- July 1, 2017)