Speaker: Bill Kahler, DClinDent., Ph.D.|Regenerative endodontic treatment of immature teeth is now advocated as first treatment choice for immature teeth with pulp necrosis. Traditionally, calcium hydroxide apexification and more recently MTA apical barrier techniques are alternative approaches. A disadvantage of these approaches is no further root development and a belief that calcium hydroxide may weaken teeth.

Speakers: Ashraf F. Fouad, D.D.S., M.S.;Anibal Diogenes, D.D.S., M.S., Ph.D.; Mahmoud Torabinejad, D.MD, M.S.D., PhD| This presentation will address the preliminary microbiological findings in immature teeth with pulp necrosis, the effectiveness of various clinical disinfection and medication protocols, and the differences in microbiological findings in cases with and without clinical success of treatment.​

Speakers: Anil Chandra, MDS| Normal human impacted third molars were collected from adults (19–29 years of age). The crowns of immature human premolars extracted for orthodontic reasons in 12- to 14- year old patients were sectioned, the dental pulps were carefully removed without touching the predentin.

Speaker: Su-Min Lee, D.D.S., M.S., D.S.cD.|This presentation will review the perspectives in disinfection protocols for regenerative endodontic procedures.

Speaker: Avina Paranjpe, B.D.S., M.S.D., M.S., Ph.D.|This is important to understand as the success of REPs depends on SCAP survival and ability to differentiation among other factors. Hence, it is imperative to identify compounds that can help SCAP differentiate thereby helping our regenerative procedures. N-acetyl cysteine (NAC) is an effective anti-oxidant and differentiation agent. SCAP in combination with NAC has shown promising results helping these cells to survive and differentiate. This differentiation could possibly increase the success rates of REPs.​

Speaker: George Huang, D.D.S., M.S.D., D.Sc.| This presentation attempts to provide updated knowledge on the current understanding of dental pulp stem cells, oral stem cells and the ongoing research.

Speaker: Jerome J. Cymerman, D.M.D.| This presentation will describe an enhanced revision of endodontic regenerative therapy to treat non-vital or previously treated open apex teeth. This incorporates the addition of a bovine collagen-carbonate apatite scaffold to the currently established regenerative endodontic technique.

Speakers: George Huang and Adham A. Azim| It has been long recognized that the key to endodontic success is largely determined by how well the root canal system is disinfected. To render the canal bacteria-free is challenging. Mechanical debridement alone is limited in reaching all the root canal spaces.

Speakers: Anibal Diogenes, D.D.S., M.S., Ph.D., Avina Paranjpe, B.D.S., M.S.D., M.S., Ph.D. and Domenico Ricucci, D.D.S., MD | Regenerative endodontic procedures aim to form a vital tissue into an empty but infected root canal space that restores the lost functions of the native dental pulp. These procedures have been shown to promote healing of apical periodontitis and further root development by the deposition of hard tissue and continued root development in immature permanent teeth with necrotic pulp and apical periodontitis/abscess.

Speaker: Sahng Gyoon Kim, D.D.S., M.S.| This lecture will systematically review the properties and biological performance of biomaterial scaffolds utilized in clinical trials and animal studies. Additionally, the histological outcomes of regenerative endodontic treatment in animal models using different scaffolds will be presented based on the findings from the author’s laboratory. The potential application of biological scaffolds for clinical regenerative endodontic therapy will also be discussed for practitioners.​